BUFFALO, N.Y. — A decade ago, University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington’s disease?

Preliminary results from a small trial offer the clearest evidence yet that the brain disease’s progression can be slowed. A one-time gene therapy can markedly slow the progression of Huntington’s ...

Scientists may have discovered the first therapy for Huntington’s disease, a brain disorder that until now has had no effective treatments. Researchers at the University of College London (UCL) ...

This image shows three brain cells with the faulty protein that causes Huntington’s disease. The bright yellow cell in the middle has built up a clump of this protein inside it. The blue spots in the ...

Even hearing the phrase “Huntington’s disease” will make a room suddenly somber. So the joy that accompanied a recent announcement of results of an experimental gene therapy for the deadly diseases ...

Sept. 24 (UPI) --Researchers at University College London reported success in treating Huntington's disease with gene therapy, which is the world's first to prove successful. The gene therapy slowed ...

A gene therapy injected into patients’ brains slowed progression of the disease by 75 percent, preliminary findings reported. By Dana G. Smith Preliminary results from a small clinical trial to treat ...

Huntington’s disease is a neurological (brain) condition that causes involuntary movement, changes to emotions, behavior, and thinking. Huntington’s is a genetic disease that worsens over time.

Every week neurologist Victor Sung sees people with Huntington’s disease, a rare and deadly neurodegenerative disorder, at his clinic at the University of Alabama at Birmingham. But a Wednesday in ...

A new medical trial showed promising results as scientists seek a breakthrough to treat Huntington's disease, according to research team based in the United Kingdom. The clinical drug trial by ...

Researchers found that inhibiting GSK-3 led to less defects in the axonal transport process and less neuronal cell death, while inhibiting ERK1 led to more transport problems and more cell death. A ...