A new gene therapy reversed heart failure in pigs by repairing heart function through cBIN1, showing major promise for future ...

New Gene Therapy Reverses Heart Failure in Large Animal Model Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart ...

A gene therapy for heart failure being developed by Bayer’s AskBio unit has been granted fast-track status by the FDA, shortly after it showed preliminary signs of efficacy in a phase 1 trial.

The laboratory experiment used a virus to carry a restorative gene into cells taken from people with congestive heart failure. The gene blocked the activity of an enzyme that contributes to the ...

Bayer’s AskBio gene therapy unit has started recruiting patients into a phase 2 trial of its AB-1002 candidate for congestive heart failure (CHF), buoyed by encouraging data from a first-in ...

On Thursday, the startup unveiled $65 million to begin human testing with a lead therapeutic candidate that could demonstrate this approach in a type of heart failure. “We need to think about ...

Of these, the total rate of death and adverse events was lower in the cell-therapy group than in the sham group (20.3% vs 31.7%; P = .17). Also, when the Minnesota Living With Heart Failure ...

Nuevocor is developing a one-time gene therapy for heart failure patients. Inovio taking on Covid again, almost 3 years after abandoning vaccine CEO says biotech firm is on path to $1B in revenue ...

Iron therapy may reduce the risk of heart failure hospitalization and cardiovascular death in patients with CKD, according to a meta-analysis of randomized trials. Iron therapy for chronic kidney ...

One of these lead assets is LX2006, an AAV-based gene therapy designed to treat patients with Friedreich's ataxia hypertrophic cardiomyopathy, by increasing expression of the heart muscle protein ...

Researchers have developed a new therapy that can be injected intravenously right after a heart attack to promote healing and prevent heart failure ... in the Shu Chien-Gene Lay Department ...

The main cause of Gene Hackman's death was heart ... documents the 95-year-old actor's poor heart health, noting he had experienced congestive heart failure, an aortic valve replacement and ...