PD-1/LAG-3 molecular mechanism of co-signaling was identified in T-cells, and combination of CBL-B inhibitors with anti-PD-1/anti-LAG-3 immunotherapies overcame PD-1/LAG-3-mediated resistance in ...
ZIKV exhibits a high neurotropism and poses significant risks to the developing nervous system. We show that inhibition of ...
The inhibitors CK-666 and CK-869 have different inhibitory effects on Arp2/3 complex mediated actin assembly depending on the ...
Neutrophils may be dynamically trained into divergent and distinct functional phenotypes, which may bear fundamental ...
The IRE1α/XBP1 arm of the unfolded protein response promotes myoblast fusion during skeletal muscle regeneration and overload ...
In a variety of infections, bacteria form multicellular communities which contribute to virulence and antibiotic tolerance. The molecular biology of such communities is actively studied, but our ...
The EMBO member Antonello Covacci was born on 14 December 1957 in Tuscania, a town near Rome that, in antiquity, played a ...
Senescent cells are characterized by DNA damage, but the underlying mechanisms in many contexts remain little understood. Our ...
In this article, the author’s name ‘Linda Stefenatti’ was incorrectly written as ‘Linda Stefanatti’. The original article has been corrected.
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The monomer-binding protein profilin 1 (PFN1) ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...