In three total drafts as the team's lead front office decision-maker, Holmes has selected five Pro Bowlers, including a pair of All-Pros (offensive tackle Penei Sewell and receiver Amon-Ra St. Brown). Additionally, he's done so while consistently taking the best player available on his and Detroit's draft board, instead of drafting based on need.

The 2023 season saw the Detroit Lions win their division for the first time in 30 years (when their division was known as the NFC Central), and win a playoff game for the first time in just as long.