Numerous other topical agents may be used for treating AD. Topical antibiotics, such as mupirocin ointment 2% applied b.i.d., may be effective in AD by reducing staphylococcal colonization.
Vancomycin, for example, has a pH of 2.5–4.5, which helps to explain its potential for extravasation. Medications with alkalotic pH (> 7.45) can be just as damaging to tissue. One example is ...